• Femarelle Rejuvenate supplement packaging on a green background
  • Femarelle Rejuvenate supplement packaging with text on a white background
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  • The clinically studied, non-hormonal supplement for perimenopause, trusted for over 25 years across 40+ countries.

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Femarelle Rejuvenate

Femarelle Rejuvenate

CAD $49.99
CAD $49.99
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Find your fit

Which stage are you in?

40sPerimenopause 50sMenopause 60sPostmenopause

A non-hormonal, clinically studied supplement that helps support your energy, skin and hair, and sleep through perimenopause, so you can feel like yourself again.

The fatigue coffee can't fix

Femarelle Rejuvenate supports energy metabolism through DT56a, Biotin and Vitamin B2, helping with the kind of persistent tiredness that often starts years before menopause itself.

Skin, hair & nails

Helps maintain and support the health of skin, hair and nails through the perimenopause transition. It is one of the first changes many women notice, and one of the most reassuring to see settle.

Sleep that comes easier

Helps relieve the insomnia and interrupted sleep patterns associated with the menopause transition, so the nights stop adding to the daytime fatigue.

A woman in a calm, grounded moment
Clinical evidence

Backed by 18+ published studies

25+years

Of safety data across 40+ countries with zero significant adverse reactions reported. Available since 2000. Endorsed by the European Society of Gynecology.

01

Post-marketing survey of 2,863 women across 8 countries confirmed significant relief of fatigue, mood, and sleep disruption within the first month.

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02

12-month safety study confirmed no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.

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How it works

A different kind of compound

Femarelle works through DT56a, a compound that acts only where your body needs it. It activates estrogen receptors in the brain and bone, the systems behind energy, mood and sleep, while staying inactive in breast and uterine tissue.

Active where you need it
Brain and bone, supporting energy, mood, sleep and bone density.
Inactive where you don't
No effect on breast or uterine tissue.

Non-hormonal: it does not add estrogen and does not change your FSH or estradiol levels. Clinical safety data shows no effect on mammography or blood profile.

Understand what's happening in my 40s →

Common questions

No. Femarelle's proprietary manufacturing process creates DT56a, a unique compound with clinically validated SERM properties. Standard soy isoflavone supplements do not have this mechanism. DT56a has been validated across 18+ published studies as a distinct compound.
No. Femarelle is a natural, non-hormonal supplement. Although DT56a interacts with estrogen receptors, it does not contain estrogen and does not alter your hormonal blood profile. Clinical studies confirm that FSH and estradiol levels remain unchanged during use.
Many women report improvement within the first two weeks, with significant relief within the first month. Clinical studies show continued improvement through 12 months of use. Individual experiences vary and consistency is key.
Perimenopause can begin in your early 40s, sometimes even in your late 30s. Signs include unexplained fatigue, mood shifts, changes in skin and hair, sleep disruption, and irregular cycles. Many women don't realize these symptoms are related to hormonal changes. If you are experiencing these, Rejuvenate is formulated for this stage.
No interactions with other products have been observed in over 25 years of use across 40+ countries. Clinical studies indicate no effect on thyroid function or thyroid treatment. For specific concerns, consult your healthcare practitioner.
Femarelle has been available since 2000 and used by women in over 40 countries. To date, no significant adverse reactions have been reported. Clinical safety data through 12 months confirms no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.
Take one capsule in the morning and one in the evening. Rejuvenate can be taken with or without food. Take it a few hours before or after other medications or natural health products.
What's inside

Ingredients & usage

Recommended use

Femarelle® Rejuvenate helps support energy, healthy skin, hair and nails, and relief of insomnia associated with perimenopause.

Recommended dose

Adult women (40+): take 1 capsule with or without food twice daily, in the morning and evening.

56 capsules per box, a one-month supply.

Medicinal ingredients (per capsule)

DT56a, fermented soybean extract (Glycine max) 322 mg
Riboflavin (Vitamin B2) 1 mg
Biotin 100 mcg

DT56a is a unique compound created through proprietary manufacturing, not a standard isoflavone extract.

Non-medicinal ingredients

Flaxseed, gelatin.

Hormone free and manufactured under strict cGMP conditions. NPN 80125189.

Contraindications

Not for use during pregnancy or breastfeeding. Do not take if you are allergic to soybean, soy products or flaxseed.

Cautions and warnings

Keep out of the reach of children. Capsules are individually sealed in blister packs; do not use if the seal is broken. Consult a health care practitioner if symptoms persist or worsen. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort or tenderness, or a recurrence of menstruation or uterine spotting.

Storage

Keep under normal storage conditions, at room temperature. Consult a healthcare practitioner before use.

Health Canada NPN 80125189
18+ clinical studies
Trusted in 40+ countries
Non-hormonal

Femarelle Rejuvenate is a natural health product licensed by Health Canada (NPN 80125189). This information is not medical advice and is not intended to diagnose, treat, cure or prevent any disease. Consult a healthcare practitioner before use, especially if you take medication or have a health condition.

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