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    Femarelle® Rejuvenate

    You're not imagining it. Your body is changing.

    The fatigue coffee can't fix. The mood shifts that came out of nowhere. These changes are real — and they often start years before menopause.

    Which stage are you in?

    Sound familiar?

    Many women in their 40s notice some or all of these.

    Fatigue that doesn't lift with rest
    Mood shifts you can't quite explain
    Skin and hair changes you've started noticing
    Sleep that comes harder than it used to
    Perimenopause can begin up to 10 years before menopause. Most women don't realize that's what's happening — and that there's meaningful, non-hormonal support for this stage.

    Why Femarelle is different

    DT56a — a new class of menopause support.

    Activates estrogen receptors in brain and bone — where you need support — while blocking activity in breast and uterine tissue.

    Hormonal blood profile stays unchanged. Femarelle does not contain estrogen or alter FSH or estradiol levels.

    If soy supplements disappointed you, DT56a is fundamentally different — a unique compound, not an isoflavone extract.

    How DT56a works

    Selective support, exactly where you need it.

    Unlike hormones that affect your whole body, DT56a acts selectively — only where it's helpful, never where it isn't.

    Activates · brain & bone

    Energy, mood, sleep, bone density.

    Blocks · breast & uterine

    No effect on tissue, mammography, or blood profile.

    Endorsed as first-line therapy by the European Society of Gynecology.

    DT56a works as a Selective Estrogen Receptor Modulator (SERM) — it forms a protein in designated tissues that mimics the bonding of estrogen to a co-activator, motivating a response. In breast and uterine tissue, it instead mimics estrogen binding to a co-repressor, blocking any proliferative response. Clinical studies confirm this selectivity through 12 months of continuous use.

    Woman in a calm, grounded moment — soft natural setting

    What you're getting

    One capsule, twice a day.

    Femarelle Rejuvenate box — 56 capsules

    The benefits

    Helps maintain and support skin, hair and nail health during the perimenopause transition.

    Supports energy metabolism with DT56a, Biotin and Vitamin B2.

    Relief of insomnia and interrupted sleep patterns associated with the menopause transition.

    What's inside

    322 mg fermented soybean extract (Glycine max) per capsule. A unique compound created through proprietary manufacturing — not a standard isoflavone.

    Support energy metabolism and the maintenance of healthy skin, hair and nails.

    Recommended use

    Femarelle® Rejuvenate helps support energy, healthy skin, hair and nails, and relief of insomnia associated with perimenopause.

    Recommended dose

    Adult women (40+): Take 1 capsule with or without food twice daily in the morning and evening.

    Medicinal ingredients (per capsule)

    Fermented soybean extract (Glycine max)322 mg
    Riboflavin (Vitamin B2)1 mg
    Biotin100 mcg

    Non-medicinal ingredients

    Flaxseed, gelatin.

    Product details

    56 capsules · NPN: 80125189

    Femarelle Rejuvenate is not an isoflavone extract, is hormone free and is manufactured under strict cGMP conditions.

    Contraindications: Not for use during pregnancy or breastfeeding. Do not take if you are allergic to soybean, soy products or flaxseed.
    Cautions and warnings: Keep out of the reach of children. Capsules are individually sealed in blister packs. Do not use if the seal is broken. Consult a health care practitioner if symptoms persist or worsen. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort, and/or tenderness, or if you experience a recurrence of menstruation and/or uterine spotting.
    Storage: Keep under normal storage conditions, room temperature.
    Consult a healthcare practitioner before use.
    🍁 Health Canada NPN 80125189
    🔬 18+ clinical studies
    🌍 Trusted in 40+ countries
    💊 Non-hormonal

    Take back your energy, your skin, your sleep.

    56 capsules · 1-month supply · One capsule twice daily

    See pricing options
    🚚 Free shipping options ↩️ 60-day returns 🔒 Secure checkout

    Clinical evidence

    Backed by 18+ published studies.

    25+
    years

    Of safety data across 40+ countries with zero significant adverse reactions reported. Available since 2000. Endorsed by the European Society of Gynecology.

    01

    Post-marketing survey of 2,863 women across 8 countries confirmed significant relief of fatigue, mood, and sleep disruption within the first month.

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    02

    12-month safety study confirmed no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.

    View source

    ★★★★★

    What women are saying.

    Real results from real women

    Common questions

    No. Femarelle's proprietary manufacturing process creates DT56a — a unique compound with clinically validated SERM properties. Standard soy isoflavone supplements do not have this mechanism. DT56a has been validated across 18+ published studies as a distinct compound.
    No. Femarelle is a natural, non-hormonal supplement. Although DT56a interacts with estrogen receptors, it does not contain estrogen and does not alter your hormonal blood profile. Clinical studies confirm that FSH and estradiol levels remain unchanged during use.
    Many women report improvement within the first two weeks, with significant relief within the first month. Clinical studies show continued improvement through 12 months of use. Individual experiences vary — consistency is key.
    Perimenopause can begin in your early 40s — sometimes even late 30s. Signs include unexplained fatigue, mood shifts, changes in skin and hair, sleep disruption, and irregular cycles. Many women don't realize these symptoms are related to hormonal changes. If you're experiencing these, Rejuvenate is formulated for this stage.
    Rejuvenate for your 40s (perimenopause): fatigue, skin changes, mood, sleep. Recharge for your 50s (menopause): hot flashes, night sweats, sleep disruption. Unstoppable for your 60s+ (post-menopause): bone health, vaginal health, energy. You can also combine two Femarelle products if you experience symptoms from multiple stages.
    No interactions with other products have been observed in over 25 years of use across 40+ countries. Clinical studies indicate no effect on thyroid function or thyroid treatment. For specific concerns, consult your healthcare practitioner.
    Femarelle has been available since 2000 and used by women in over 40 countries. To date, no significant adverse reactions have been reported. Clinical safety data through 12 months confirms no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.
    There are no restrictions on duration of use. Long-term data from 40+ countries since 2000 confirms Femarelle can be taken safely without limitation. The longer you take it, the more sustained the benefits.
    Take one capsule in the morning and one in the evening. Rejuvenate can be taken with or without food. Take a few hours before or after other medications or natural health products.

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    Femarelle Rejuvenate

    Femarelle Rejuvenate

    Regular price CAD $49.99
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