• Femarelle Rejuvenate supplement packaging on a green background
  • An informational graphic with the headline 'What to expect' on a soft beige background. It includes a teal progress-style timeline marking Week 4, Week 8, and Week 12 with supporting text about gradual, steady support and clinical study.
  • Promotional graphic for Femarelle DT56a with text reading 'Non-hormonal by design' and bullet points about plant-based soy derivation, selective action, and lack of effect on breast or uterine tissue, alongside green soybeans and pods on a soft beige background.
  • Three Femarellre supplement boxes are displayed on a beige background with marketing text and a small green leaf sprig. The boxes are labeled Recharge, Antistoppable, and Rejurer, with different color designs.
  • Femarelle Rejuvenate supplement packaging with text on a white background
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You're tired in a way sleep doesn't fix. Being told you're too young for this shouldn't leave hormones as the only way forward.

There is another way forward. Femarelle Rejuvenate supports energy metabolism, healthy skin, hair and nails, and helps relieve insomnia through the menopause transition, with DT56a, plant-based and non-hormonal. Nothing about your hormone levels changes.

Se-cure

Femarelle Rejuvenate

Femarelle Rejuvenate

CAD $48.00
CAD $48.00
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40sPerimenopause 50sMenopause 60sPostmenopause
Symptoms

What Rejuvenate is made for

Tired in a way sleep does not fix

It starts years before anyone calls it menopause, and an early night does not touch it. Femarelle Rejuvenate helps support energy through the perimenopause years, with DT56a alongside biotin and vitamin B2.

Awake at three, with a full day ahead

Falling asleep is rarely the problem. Staying asleep is. Femarelle Rejuvenate helps relieve the insomnia associated with perimenopause, so the nights stop feeding the tiredness.

Hair in the brush, skin that behaves differently

Often the first change noticed, and the one that is hardest to explain away. Femarelle Rejuvenate helps support healthy skin, hair and nails through the transition.

What to expect

How soon women notice a change

The first changes

In a post-marketing survey of 2,863 women across eight countries, symptoms began easing within the first two weeks of taking Femarelle.

POMMSIS post-marketing survey

Better days, and better nights

By week four, 80% of women reported a better quality of life and 69% reported better sleep.

Post-marketing survey, 2,080 women

Full effect, and it holds

Relief reaches its full level by twelve weeks, and was unchanged when the same women were measured again at twelve months.

Yoles et al., 2004

Individual experiences vary. Taking it consistently, morning and evening, matters more than anything else.

A woman in a calm, grounded moment
Clinical evidence

Backed by 18+ published studies

25+years

Of safety data across 40+ countries with zero significant adverse reactions reported. Available since 2000. Endorsed by the European Society of Gynecology.

01

Post-marketing survey of 2,863 women across 8 countries confirmed significant relief of menopausal symptoms, including sleep disruption, within the first month.

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02

12-month safety study confirmed no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.

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How it works

A different kind of compound

Femarelle works through DT56a, a compound that acts only where your body needs it. It activates estrogen receptors in the systems behind sleep, energy, and skin and hair, while staying inactive in breast and uterine tissue.

Active where you need it
The systems behind sleep, energy, and healthy skin, hair and nails.
Inactive where you don't
No effect on breast or uterine tissue.

Non-hormonal: it does not add estrogen and does not change your FSH or estradiol levels. Clinical safety data shows no effect on mammography or blood profile.

Understand what's happening in my 40s →

Common questions

No. Femarelle's proprietary manufacturing process creates DT56a, a unique compound with clinically validated SERM properties. Standard soy isoflavone supplements do not have this mechanism. DT56a has been validated across 18+ published studies as a distinct compound.
No. Femarelle is a natural, non-hormonal supplement. Although DT56a interacts with estrogen receptors, it does not contain estrogen and does not alter your hormonal blood profile. Clinical studies confirm that FSH and estradiol levels remain unchanged during use.
Many women report improvement within the first two weeks, with significant relief within the first month. Clinical studies show continued improvement through 12 months of use. Individual experiences vary and consistency is key.
Perimenopause can begin in your early 40s, sometimes even in your late 30s. Signs include changes in skin and hair, sleep disruption, and irregular cycles. Many women don't realize these symptoms are related to hormonal changes. Rejuvenate is formulated for this stage.
No interactions with other products have been observed in over 25 years of use across 40+ countries. Clinical studies indicate no effect on thyroid function or thyroid treatment. For specific concerns, consult your healthcare practitioner.
Femarelle has been available since 2000 and used by women in over 40 countries. To date, no significant adverse reactions have been reported. Clinical safety data through 12 months confirms no changes to endometrial thickness, mammography, hormonal blood profile, or lipid levels.
Take one capsule in the morning and one in the evening. Rejuvenate can be taken with or without food. Take it a few hours before or after other medications or natural health products.
What's inside

Ingredients & usage

Recommended use

Femarelle® Rejuvenate helps relieve symptoms associated with menopause such as insomnia, interrupted sleep pattern, painful intercourse and vaginal dryness, and thereby helps improve quality of life. It helps support healthy skin, hair and nails, and helps in energy metabolism.

Recommended dose

Adult women (40+): take 1 capsule with or without food twice daily, in the morning and evening.

56 capsules per box, a one-month supply.

Medicinal ingredients (per capsule)

DT56a, fermented soybean extract (Glycine max) 322 mg
Riboflavin (Vitamin B2) 1 mg
Biotin 100 mcg

DT56a is a unique compound created through proprietary manufacturing, not a standard isoflavone extract.

Non-medicinal ingredients

Flaxseed, gelatin.

Hormone free and manufactured under strict cGMP conditions. NPN 80125189.

Contraindications

Not for use during pregnancy or breastfeeding. Do not take if you are allergic to soybean, soy products or flaxseed.

Cautions and warnings

Keep out of the reach of children. Capsules are individually sealed in blister packs; do not use if the seal is broken. Consult a health care practitioner if symptoms persist or worsen. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort or tenderness, or a recurrence of menstruation or uterine spotting.

Storage

Keep under normal storage conditions, at room temperature. Consult a healthcare practitioner before use.

Health Canada NPN 80125189
18+ clinical studies
Trusted in 40+ countries
Non-hormonal

Femarelle Rejuvenate is a natural health product licensed by Health Canada (NPN 80125189). This information is not medical advice and is not intended to diagnose, treat, cure or prevent any disease. Consult a healthcare practitioner before use, especially if you take medication or have a health condition.

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